This seems especially true for the genetic alphabet: the constraints on base pairing make it difficult to imagine an alphabet consisting of, for example, eight letters.

Some letters in the alphabet are workhorses, showing up everywhere and often, while others (looking at you, “Z”) are much rarer. But just where does each letter appear with the most frequency ...

In letter mode, you can tap on any letter in the alphabet for a screen featuring a colorful drawing of an animal whose name starts with that letter.

‘Alphabet Topography’ is a beautiful look at how often letters are used “Alphabet Topography,” a piece from Yale graduates Caspar Lam and YuJune Park of the Synoptic Office design studio ...