The San Francisco 49ers are dealing with a rash of injury issues entering their Week 2 matchup with the New Orleans Saints.

The team is off Monday and Tuesday, then they'll be back on the practice field Wednesday. The 49ers and Saints will kick off at 10:00am Pacific Time from the Superdome in New Orleans. More 49ers: ...

The San Francisco 49ers defeated the Seattle Seahawks on Sunday, and defensive end Nick Bosa gave a lot of credit to his ...

The San Francisco 49ers defeated the Seattle Seahawks on Sunday. Here's who had the best and worst days, according to Pro Football Focus.

The San Francisco 49ers have been very thin at wide receiver throughout the preseason and into Week 1. Now, they're bringing in more help.

Riding high off the win, the 49ers turned around and gave starting offensive tackle Colton McKivitz a three-year, $45 million extension with $27 million guaranteed, according to ESPN's Adam Schefter.

The San Francisco 49ers haven't tried out any kickers, but that doesn't mean they'll move forward with Jake Moody.

The San Francisco 49ers have a thin wide receiver room, and they lost another key member of the room on Sunday, as Jauan Jennings was injured.

Moody's miss morphed into a rapid momentum-shifter as the Seahawks proceeded to mount an eight-play, 50-yard scoring drive that ended with 48-yard field goal from Seattle kicker Jason Myers to carry a ...

San Francisco 49ers tight end George Kittle made an impact early in Week 1, but he suffered an injury in the first half.

The San Francisco 49ers will have a full complement of offensive weapons when they face the Seattle Seahawks in Week 1.

The San Francisco 49ers kick off their quest to return to the postseason with an NFC West showdown against the Seattle Seahawks on Sunday.